論文

  • Y. Koyama, Y. Kobayashi, I. Hirota, Y. Sun, I. Ohtsu, H. Imai, Y. Yoshioka, H. Yanagawa, T. Sumi, H. Kobayashi, S. Shimada.
    A new therapy against ulcerative colitis via the intestine and brain using the Si-based agent.
    Sci. Rep. 12 (2022) 9634,
    https://doi.org/10.1038/s41598-022-13655-7.
  • N. Otani, K. Tomita, Y. Kobayashi, K. Kuroda, Y. Koyama, H. Kobayashi, and T. Kubo.
    Hydrogen-generating Si-based agent protects against skin flap ischemia- reperfusion injury in rats.
    Sci. Rep. (2022) 12:6168.
  • N. Usui, K. Matsumoto-Miyai, Y. Koyama, Y. Kobayashi, Y. Nakamura, H. Kobayashi, and S. Shimada.
    Social communication of maternal immune activation affected offspring is improved by Si-based hydrogen-producing agent,
    Frontiers Psychiatry, (2022) 13:872302.
    https://doi.org/10.3389/fpsyt.2022.872302.
  • N. Usui, S. Togawa, T. Sumi, Y. Kobayashi, Y. Koyama, Y. Nakamura, M. Kondo, K. Shinoda, H. Kobayashi, and S. Shimada.
    Si-based hydrogen-producing nanoagent protects fetuses from miscarriage caused by mother-to-child transmission.
    Front. Med. Technol. 3 (2021) 665506.
    doi: 10.3389/fmedt.2021.665506.
  • Y. Kobayashi, S. Fujie, K. Imamura, and H. Kobayashi.
    Structure and hydrogen generation mechanism of Si-based agent.
    Appl. Surf. Sci. 536 (2021) 147398.
    [DOI: 10.1016/j.apsusc.2020.147398]
  • Y. Kobayashi, Y. Kowada, T. Shirohata, and H. Kobayashi.
    Changes in structure and surface properties of Si-based agent during hydrogen generation reaction.
    Appl. Surf. Sci. 535 (2021) 147361.
    [DOI: 10.1016/j.apsusc.2020.147361]
  • Y. Inagaki, S. Fukuhara, R. Imamura, Y. Kobayashi, S. Kuribayashi, K. Okada, Y. Sekii, K. Takezawa, H. Kiuchi, M. Uemura, H. Kobayashi, and N. Nonomura.
    Novel hydrogen-producing Si-based agent reduces oxidative stress, improves sperm motility and in vitro fertilization rate in varicocele.
    Andrology 9 (2021) 376-383.
  • R. Imamura, M. Kawamura, A. Taniguchi, Y. Kobayashi, S. Nakazawa, T. Kato, T. Abe, M. Uemura, H. Kobayashi, and N. Nonomura.
    Efficacy of a Si-based agent against developing renal failure in a rat remnant kidney model, Biochem. Biophys.
    Res. Commun. 533 (2020) 698-703.
    [DOI: 10.1016/j.bbrc.2020.10.067]
  • M. Kawamura, R. Imamura, Y. Kobayashi, A. Taniguchi, S. Nakazawa, T. Kato, T. Namba, T. Abe, H. Kobayashi, and N. Nonomura.
    Oral administration of nano-sized silicon particles attenuates oxidative stress and ischemia-reperfusion injury in a rat model: A novel hydrogen administration method.
    Transplantation 104(S3) (2020) S164.
    [DOI: 10.1097/01.tp.0000699168.59819.ce]
  • Y. Kobayashi, R. Imamura, Y. Koyama, M. Kondo, H. Kobayashi, and S. Shimada. Renoprotective and neuroprotective effects of enteric hydrogen generation from Si-based agent.
    Sci. Rep. (2020) 10:5859.
    [DOI: 10.1038/s41598-020-62755-9] (Open access)
  • M. Kawamura, R. Imamura, Y. Kobayashi, A. Taniguchi, S. Nakazawa, T. Kato, T. Abe, H. Kobayashi, and N. Nonomura.
    PD-22-04 Oral administration of nano-sized silicon particles regulates gene expression related to oxidative stress and suppresses rat renal ischemia-reperfusion injury.
    J. Urology (2020) 203:e460.
  • M. Kawamura, R. Imamura, Y. Kobayashi, A. Taniguchi, S. Nakazawa, T. Kato, T. Namba-Hamano, T. Abe, M. Uemura, H. Kobayashi and N. Nonomura.
    Oral administration of Si-based agent attenuates oxidative stress and Ischemia-reperfusion injury in a rat model: A novel hydrogen administration method.
    Front. Med., 7(95) (2020) 1-10.
    [DOI: 10.3389/fmed.2020.00095]
  • 小林悠輝、小林　光、今村亮一、島田昌一
    シリコン製剤による体内水素発生と医薬応用
    The Chemical Times, 254号 (2019) 2-7. (Open access)
  • Y. Kobayashi.
    Hydrogen generation by reaction of Si nanopowder with water for medical use.
    J. Nanomater. Mol. Nanotechnol. 7 (2018) 42.
    [DOI: 10.4172/2324-8777-C2-023]
  • Y. Kobayashi, K. Imamura, T. Matsumoto, and H. Kobayashi.
    Fabrication of Si nanopowder and application to hydrogen generation and photoluminescent material.
    J. Elect. Eng. 68 (2017) 17-23.
  • K.Imamura. Y.Kobayashi. S.Matsuda. T.Akai H.Kobayashi.
    Reaction of Si nanopowder with water investigated by FT-IR and XPS
    AIP Adv. 7 (2017) 085310-1-10. (Open Access)
  • Y. Kobayashi, S. Matsuda, K. Imamura, and H. Kobayashi.
    Hydrogen generation by reaction of Si nanopowder with neutral water.
    J. Nanopart. Res. 19 (2017) 176-1-9.
  • Yuki Kobayashi. Shinsuke Matsuda. Kentaro Imamura.　Hikaru　Kobayashi.
    Hydrogen generation by reaction of Si nanopowder with neutral water
    J. Nanopart. Res. 19 (2017) 176-1-9.　(Open Access)

著書・総説・解説

  • 小林悠輝、小林　光、島田昌一、今村亮一、
    シリコン製剤による体内水素発生と酸化ストレス疾患の予防・治療、
    月刊BIO INDUSTRY、38(6)（2021）32-45.
  • Y. Kobayashi, H. Kobayashi.
    Theoretical Chemistry for Advanced Materials.
    Springer Nature 2020, pp. 353-382..
  • V. H. Carvalho-Silva, E. C. Vaz, N. D. Couninho, H. Kobayashi, Y. Kobayashi, T. Kasai, F. Falazzetti, A. Lombardi, and V. Aquilanti.
    The increase of the reactivity of molecular hydrogen with hydroxyl radical from the gas phase versus and aqueous environment: Quantum chemistry and transition state-theory calculations – Computational Science and its Application.
    Springer (ICCSA) (2019) 450-459.
  • Y. Kobayashi and H. Kobayashi.
    Springer Nature, Theoretical Chemistry for Advanced Nanomaterials – Functional Analysis by Computation and Experiment.
    Si nanopowder for photoluminescence and hydrogen generation materials, (2019) 353-382.
  • 小林光，喜村勝矢，藤江俊太，小林悠輝，今村健太郎、
    シリコン切粉から創製するシリコンナノ粒子と水との反応による水素発生技術
    燃料電池15 (2016) 59-62.

国際会議プロシーディング 

  • Y. Kobayashi, H. Kobayashi, S. Shimada, and R. Imamura.
    Internal hydrogen generation and a decrease in oxidative stress by Si-based agent. AIP Conference Proceedings 2343 (2021) 020011.
    https://doi.org/10.1063/5.0048487.
  • Y. Kobayashi.
    Hydrogen generationby reaction of Si nanopowder with water for medical use.
    J. Nanomater. Mol. Nanotechnol. 7 (2018) 42.
    [DOI: 10.4172/2324-8777-C2-023]
  • Y. Kobayashi and H. Kobayashi.
    High amount of hydrogen generation by the reaction of Si composition with water in the body to prevent oxidative stress-induced diseases.
    Proceedings of 10th Solid State Surface and Interfaces, (2018) (2)-(4).
  • Y. Kobayashi, S. Fujie, K. Imamura, and H. Kobayashi.
    Hydrogen generation by reaction of Si nanopowder with neutral water and medical application.
    Progress in Applied Surface, Interface, and Thin Film Science- Solar Renewable Energy News 2017, (2017) 74-76.
  • Y. Kobayashi, S. Matsuda, K. Imamura, and H. Kobayashi.
    Hydrogen-rich water produced by the reaction of Si nanopowder with water.
    Proceeding sof Progress in Applied Surface, Interface, and Thin Film Science 2015, (2015) 79-80.