Y. Koyama, Y. Kobayashi, I. Hirota, Y. Sun, I. Ohtsu, H. Imai, Y. Yoshioka, H. Yanagawa, T. Sumi, H. Kobayashi, S. Shimada. A new therapy against ulcerative colitis via the intestine and brain using the Si-based agent. Sci. Rep. 12 (2022) 9634, https://doi.org/10.1038/s41598-022-13655-7.
N. Otani, K. Tomita, Y. Kobayashi, K. Kuroda, Y. Koyama, H. Kobayashi, and T. Kubo. Hydrogen-generating Si-based agent protects against skin flap ischemia- reperfusion injury in rats. Sci. Rep. (2022) 12:6168.
N. Usui, K. Matsumoto-Miyai, Y. Koyama, Y. Kobayashi, Y. Nakamura, H. Kobayashi, and S. Shimada. Social communication of maternal immune activation affected offspring is improved by Si-based hydrogen-producing agent, Frontiers Psychiatry, (2022) 13:872302. https://doi.org/10.3389/fpsyt.2022.872302.
N. Usui, S. Togawa, T. Sumi, Y. Kobayashi, Y. Koyama, Y. Nakamura, M. Kondo, K. Shinoda, H. Kobayashi, and S. Shimada. Si-based hydrogen-producing nanoagent protects fetuses from miscarriage caused by mother-to-child transmission. Front. Med. Technol. 3 (2021) 665506. doi: 10.3389/fmedt.2021.665506.
Y. Kobayashi, S. Fujie, K. Imamura, and H. Kobayashi. Structure and hydrogen generation mechanism of Si-based agent. Appl. Surf. Sci. 536 (2021) 147398. [DOI: 10.1016/j.apsusc.2020.147398]
Y. Kobayashi, Y. Kowada, T. Shirohata, and H. Kobayashi. Changes in structure and surface properties of Si-based agent during hydrogen generation reaction. Appl. Surf. Sci. 535 (2021) 147361. [DOI: 10.1016/j.apsusc.2020.147361]
Y. Inagaki, S. Fukuhara, R. Imamura, Y. Kobayashi, S. Kuribayashi, K. Okada, Y. Sekii, K. Takezawa, H. Kiuchi, M. Uemura, H. Kobayashi, and N. Nonomura. Novel hydrogen-producing Si-based agent reduces oxidative stress, improves sperm motility and in vitro fertilization rate in varicocele. Andrology 9 (2021) 376-383.
R. Imamura, M. Kawamura, A. Taniguchi, Y. Kobayashi, S. Nakazawa, T. Kato, T. Abe, M. Uemura, H. Kobayashi, and N. Nonomura. Efficacy of a Si-based agent against developing renal failure in a rat remnant kidney model, Biochem. Biophys. Res. Commun. 533 (2020) 698-703. [DOI: 10.1016/j.bbrc.2020.10.067]
M. Kawamura, R. Imamura, Y. Kobayashi, A. Taniguchi, S. Nakazawa, T. Kato, T. Namba, T. Abe, H. Kobayashi, and N. Nonomura. Oral administration of nano-sized silicon particles attenuates oxidative stress and ischemia-reperfusion injury in a rat model: A novel hydrogen administration method. Transplantation 104(S3) (2020) S164. [DOI: 10.1097/01.tp.0000699168.59819.ce]
Y. Kobayashi, R. Imamura, Y. Koyama, M. Kondo, H. Kobayashi, and S. Shimada. Renoprotective and neuroprotective effects of enteric hydrogen generation from Si-based agent. Sci. Rep. (2020) 10:5859. [DOI: 10.1038/s41598-020-62755-9] (Open access)
M. Kawamura, R. Imamura, Y. Kobayashi, A. Taniguchi, S. Nakazawa, T. Kato, T. Abe, H. Kobayashi, and N. Nonomura. PD-22-04 Oral administration of nano-sized silicon particles regulates gene expression related to oxidative stress and suppresses rat renal ischemia-reperfusion injury. J. Urology (2020) 203:e460.
M. Kawamura, R. Imamura, Y. Kobayashi, A. Taniguchi, S. Nakazawa, T. Kato, T. Namba-Hamano, T. Abe, M. Uemura, H. Kobayashi and N. Nonomura. Oral administration of Si-based agent attenuates oxidative stress and Ischemia-reperfusion injury in a rat model: A novel hydrogen administration method. Front. Med., 7(95) (2020) 1-10. [DOI: 10.3389/fmed.2020.00095]
小林悠輝、小林 光、今村亮一、島田昌一 シリコン製剤による体内水素発生と医薬応用 The Chemical Times, 254号 (2019) 2-7.(Open access)
Y. Kobayashi. Hydrogen generation by reaction of Si nanopowder with water for medical use. J. Nanomater. Mol. Nanotechnol. 7 (2018) 42. [DOI: 10.4172/2324-8777-C2-023]
Y. Kobayashi, K. Imamura, T. Matsumoto, and H. Kobayashi. Fabrication of Si nanopowder and application to hydrogen generation and photoluminescent material. J. Elect. Eng. 68 (2017) 17-23.
K.Imamura. Y.Kobayashi. S.Matsuda. T.Akai H.Kobayashi. Reaction of Si nanopowder with water investigated by FT-IR and XPS AIP Adv. 7 (2017) 085310-1-10. (Open Access)
Y. Kobayashi, S. Matsuda, K. Imamura, and H. Kobayashi. Hydrogen generation by reaction of Si nanopowder with neutral water. J. Nanopart. Res. 19 (2017) 176-1-9.
Yuki Kobayashi. Shinsuke Matsuda. Kentaro Imamura. Hikaru Kobayashi. Hydrogen generation by reaction of Si nanopowder with neutral water J. Nanopart. Res. 19 (2017) 176-1-9. (Open Access)
Y. Kobayashi, H. Kobayashi. Theoretical Chemistry for Advanced Materials. Springer Nature 2020, pp. 353-382..
V. H. Carvalho-Silva, E. C. Vaz, N. D. Couninho, H. Kobayashi, Y. Kobayashi, T. Kasai, F. Falazzetti, A. Lombardi, and V. Aquilanti. The increase of the reactivity of molecular hydrogen with hydroxyl radical from the gas phase versus and aqueous environment: Quantum chemistry and transition state-theory calculations – Computational Science and its Application. Springer (ICCSA) (2019) 450-459.
Y. Kobayashi and H. Kobayashi. Springer Nature, Theoretical Chemistry for Advanced Nanomaterials – FunctionalAnalysis by Computation and Experiment. Si nanopowder for photoluminescence and hydrogen generation materials, (2019) 353-382.
Y. Kobayashi, H. Kobayashi, S. Shimada, and R. Imamura. Internal hydrogen generation and a decrease in oxidative stress by Si-based agent. AIP Conference Proceedings 2343 (2021) 020011. https://doi.org/10.1063/5.0048487.
Y. Kobayashi. Hydrogen generationby reaction of Si nanopowder with water for medical use. J. Nanomater. Mol. Nanotechnol. 7 (2018) 42. [DOI: 10.4172/2324-8777-C2-023]
Y. Kobayashi and H. Kobayashi. High amount of hydrogen generation by the reaction of Si composition with water in the body to prevent oxidative stress-induced diseases. Proceedings of 10th Solid State Surface and Interfaces, (2018) (2)-(4).
Y. Kobayashi, S. Fujie, K. Imamura, and H. Kobayashi. Hydrogen generation by reaction of Si nanopowder with neutral water and medical application. Progress in Applied Surface, Interface, and Thin Film Science- Solar Renewable Energy News 2017, (2017) 74-76.
Y. Kobayashi, S. Matsuda, K. Imamura, and H. Kobayashi. Hydrogen-rich water produced by the reaction of Si nanopowder with water. Proceeding sof Progress in Applied Surface, Interface, and Thin Film Science 2015, (2015) 79-80.